PANDAA HIVDR ReFocus Select
HIV Drug Resistance
PANDAA HIV ReFocus Select ™ allows twenty distinctive focused genotyping PANDAA assays to be used in any configuration. Individual multiplexes allow the differentiation of multiple DRMs at a single codon e.g., 82A, 82F and 82T or all three DRMs can be genotyped together using the 82AFT + 84V PANDAA. All contain the internal Viral Quantifier (VQ) to determine the relative abundance of each DRM.
Alternative and additional DRMs combinations are available upon request.
Rapid and ultrasensitive detection of drug-resistant HIV variants- Facilitates improved access to drug resistance testing in resource-limited countries
| HIV Target Region | PANDAA Multiplex Pairs | ||
|---|---|---|---|
| Reverse Transcriptase | 65R + 181C 103N + 181C | 103NS + 190A 106M + 190A | 106M + 184VI 184V + 65R |
| Protease | 47AV + 50L 88S + 65R* 76V + 65R* | 76V + 184VI* 47A + 82A 82F + 184V* | |
| Integrase | 148H + 65R* 148K + 65R* 148R + 65R* | 155H + 184V* | 118R + 263K |
* denotes a DRM in reverse transcriptase.
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